I realize that this research is only on the cancer cells, and not on people. But, I think it is fascinating. And I hope there will be follow up for those who might want to take it. Anyhow, this is it:
Ganoderma Lucidum causes apoptosis in leukemia, lymphoma and multiple myeloma cells.
(What is Apoptosis?)
Over many centuries, herbal remedies have treated a variety of ailments. This empiric observational approach has produced a number of leads for formulated medicines.
Ganoderma lucidum extract was screened for its anti-proliferative activity using a panel of 26 human cancer cell lines.
The six most sensitive hematologic cell lines were:
HL-60 (ED50 26 microg/ml),
U937 (63 microg/ml),
K562 (50 microg/ml),
Blin-1 (38 microg/ml),
Nalm-6 (30 microg/ml)
and RPMI8226 (40 microg/ml).
Cell cycle analyses revealed a G2/M arrest, most prominently in HL-60 cells.
Four hematopoietic cell lines (HL-60, Blin-1, U937, RPMI8226) were examined for apoptosis, which ranged between 21 and 92%.
After exposure to Ganoderma lucidum extract, HL-60 cells became multinucleated with an increased DNA content.
These results indicate that Ganoderma lucidum extract has a profound activity against leukemia, lymphoma and multiple myeloma cells and may be a novel adjunctive therapy for the treatment of hematologic malignancies.
Source:
Leukemia Research Journal
2006 Jul;30(7):841-8.
Epub 2006 Jan 19.
Ganoderma lucidum causes apoptosis in leukemia, lymphoma and multiple myeloma cells.
Authors:
Müller CI, Kumagai T, O'Kelly J, Seeram NP, Heber D, Koeffler HP.
Comment in
Ganoderma lucidum in cancer research. [Leuk Res. 2006]
PMID: 16423392 [PubMed - indexed for MEDLINE]
If you would like to read a full PDF article, it's HERE
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